Originally published here.
Even with shelter-in-place and stay-at-home orders set up across the country, top officials like the CDC and WHO still encourage regular exercise—and for good reason. In addition to improving your mental health, a 2019 scientific review in the Journal of Sport and Health Science found that exercise can improve your immune response, lower illness risk, and reduce inflammation.
The study looked at “acute exercise,” meaning that of moderate to vigorous intensity lasting less than an hour. (The study mainly examined walking, but that could also mean an elliptical workout, a spin class, or even a run.) Study author David Nieman, DrPH, a professor in the department of biology at Appalachian State University and director of the university's Human Performance Laboratory, tells Health that typically, people only have a small number of immune cells circulating around the body. Those cells prefer to hang out in lymphoid tissues and organs like the spleen, where your body kills viruses, bacteria, and other microorganisms that cause disease.
Because exercise increases blood and lymph flow as your muscles contract, it also increases the circulation of immune cells, making them roam the body at a higher rate and at higher numbers, says Nieman. Specifically, exercise helps to recruit highly specialized immune cells—such as natural killer cells and T cells—find pathogens (like viruses) and wipe them out. In Nieman's 2019 review, participants who took a 45-minute brisk walk experienced this uptick of immune cells floating around the body for up to three hours after the walk, Nieman explains.
While you do get an immediate response from your immune system when you exercise, that will eventually go away—unless, that is, you keep working out consistently. “If you go out for 45 minutes of exercise the next day, this all happens again,” Nieman says. “It all adds up as time goes on.” In fact, another study from Nieman and his team—this one published in 2011 in the British Journal of Sports Medicine—found that those who did aerobic exercise five or more days of the week lowered the number of upper respiratory tract infections (like the common cold) over a 12-week period by more than 40%.
Think of the lasting immune effect of exercise like this, Nieman explains: Say you have a housekeeper come over to clean your home for 45 minutes most days of the week. The house will look a lot better on that first day than if someone never came. But the more frequently the housekeeper comes back, the better and cleaner the house will look. “Exercise really is a housekeeping activity, where it helps the immune system patrol the body and detect and evade bacteria and viruses,” Nieman says. So, you can’t necessarily exercise one day here and there and expect to have an illness-clearing immune system. Come back for more movement on the regular, though, and your immune system is better prepared to wipe out sickness-causing germs. This holds up, even as you get older, according to another 2018 review article published in the journal Frontiers in Immunology.
Another benefit of exercise is that it decreases inflammation in the body—which, in turn, can also improve immunity. In fact, some research, like the 2004 study in the Journal of the American Geriatrics Society, links decreased levels of inflammatory markers to those that exercise more often and have higher fitness levels. And Nieman says that goes hand-in-hand with immunity. “When immune cells try to function with inflammation, it puts the immune system in a chronically inflamed state too,” he says, which makes it harder to fight infection. To cut down on inflammation, kick up your activity level.
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